Growth & Death
Molecules and Signalling
Protein Synthesis
ATP Production
Electrolytes
Cell Structures
Tissue Structure
Cardiac Output
Cardiac Cycle
Circulation
Special Circulations
Pulmonary Ventilation
Gas Exchange
Regulation of Respiration
Mouth
Stomach
Small Intestine
Large Intestine
Liver
Vitamins
Other
Nephron
Micturition
Regulation
Embryology
Hormones and Regulation
Fetal Physiology
Pregnancy
Components
Synapses
Sensory System
Motor System
Ocular Physiology
Thyroid and Parathyroid Glands
Adrenal Glands
The Pancreas
Hypothalamus and Pituitary
Cells of the Immune System
Innate Immune System
Adaptive Immune System
Immune Responses
Infections
Haematology
The stomach is a muscular organ located in the left upper abdomen, positioned between the oesophagus and the duodenum. As food reaches the end of the oesophagus, it enters the stomach through a muscular valve called the lower oesophageal sphincter. The stomach continues to break food down mechanically and chemically, through churning the food and secreting acid and enzymes for digestion. This allows for absorption of nutrients to occur as the food continues through the gastrointestinal tract.
The acidic environment in the stomach helps with digestion and destroys any potential pathogenic microorganisms that may have been ingested. Acid secretion is an intricate process that needs to be highly regulated. If this goes wrong, it can lead to hypersecretion of acid or achlorhydria.
Gastric mucus is also produced within the stomach. It is secreted by the epithelial cells and glandular cells in the stomach. This mucus acts as a barrier that protects the stomach wall from the acid and digestive enzymes found within the stomach lumen. If the mucus layer is breached for some reason, it can result in peptic ulcer formation which can cause various problems.
In this section, learn more about the physiology of the stomach- the production of acid, and mucus production.
by Farhana Patel
by Ade Folorunso
by Grace Fitzgerald
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