Cell Signalling and Molecular Physiology

Principles of Cell Signalling and Membrane Transport

Cell signalling and membrane transport are fundamental to physiology. Cells must detect, respond to, and communicate with their environment in order to maintain homeostasis. This section explores how molecules move across selectively permeable membranes and how cells transmit signals through receptor-mediated pathways. Understanding these mechanisms is essential for interpreting normal physiology and disease processes.

Membrane Transport and Molecular Movement

Key topics include diffusion, osmosis, and active transport, which describe how substances cross cell membranes. These processes underpin fluid balance, electrolyte regulation, and nutrient exchange. You will also find detailed explanations of endocytosis and exocytosis, which allow cells to internalise and secrete larger molecules. Together, these mechanisms form the basis of cellular transport physiology.

Receptors, Enzymes and Intracellular Signalling

This section also covers cellular receptors, G-proteins, enzyme kinetics, and enzyme inhibition. These concepts are central to understanding pharmacology, hormone action, and metabolic regulation. Designed for medical students and healthcare professionals, the content links molecular physiology to clinical practice, supporting exam preparation and deeper conceptual understanding.

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Enzyme Kinetics

Enzyme Inhibition

G-proteins

Diffusion

Osmosis

Active Transport

Endocytosis and Exocytosis

Diagram showing 2 insulin molecules binding to their receptors causing the receptor tyrosine kinases to dimerase and phosphorylate each other triggering an intracellular cascade.

Cellular Receptors

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